Geodesic Intelligence

AGI for drug discovery

Build AGI that discovers the shortest path from biology to medicines.

We combine AI, structure, and biophysics to help move from biological targets to better therapeutic candidates and better experimental decisions.

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The agent workspace for discovery teams.

NovaDDE plans, runs, and evaluates discovery work, from target to prioritized candidates, with agents grounded in biology, structure, and biophysics. It calls models — including NovaFold — as tools and documents every decision along the way.

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100+
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10+
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Designed candidates funnelling through two prioritization filters into a validation assay plate
Models

Frontier models for structure prediction and design.

Structure prediction Preview

NovaFold-Lite-Preview

A first look at our most powerful structure prediction model — a lighter, faster build we're previewing while the full model finishes training. Sequence to atomic-level structure for proteins, antibodies, and complexes.

Model card
NovaFold prediction for PDB 8vzm, resolving from a point cloud and overlaid on the deposited structure: 0.56 Å C-alpha RMSD across 642 aligned residues
NovaFold prediction for PDB 7fyr, resolving from a point cloud and overlaid on the deposited structure: 0.15 Å C-alpha RMSD across 128 aligned residues
NovaFold prediction for PDB 9avr, resolving from a point cloud and overlaid on the deposited structure: 0.62 Å C-alpha RMSD across 370 aligned residues

Have a target in progress?

NovaDDE helps you move from target definition to better experimental decisions, faster.

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